Temperature optimum (IMAGE) Uppsala University Caption View of the part of the enzyme that controls the temperature optimum. The loop region that is shown in dark blue is from the Antarctic bacterium and that shown in red from the pig enzyme. By introducing mutations into the Antarctic structure the loop could be moved towards the pig structure and the temperature optimum raised. Credit Johan Åqvist Usage Restrictions May only be published in connection to reports about the research presented in the article "Computational design of the temperature optimum of an enzyme reaction" or after permission from creator. License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.