The markers and risk stratification model of intracranial aneurysm instability in a large Chinese cohort (IMAGE)

Science China Press

The markers and risk stratification model of intracranial aneurysm instability in a large Chinese cohort

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Graphical abstract of the study. This study demonstrated that oleic acid, arachidonic acid, IL-1β, and TNF-α were dysregulated between stable and unstable UIAs. The instability classifier, incorporating radiological features and biomarkers, presents a high accuracy of predicting the risk of UIA instability and contributed to UIA risk stratification, which may help guide treatment decision-making for UIAs. UIA, unruptured intracranial aneurysm; IL-1β, interleukin 1β; TNF-α, tumor necrosis factor α.

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