Origami (Folding steps) (IMAGE)
Caption
The series of folding steps represents successive reactions. Starting from the simple cyclobutanol starting material ("piece of paper"), an isolable intermediate compound can be produced ("origami hat"). By adding a Brønsted acid activator, an intramolecular cyclisation is triggered, which leads to high value-added tetralin derivatives ("origami boat"). Alternatively, so-called nucleophiles can be introduced by activating the benzylic carbon-fluorine bond ("origami heart").
Credit
University of Münster/Gilmour Group
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Original content