Suppression of Viral Amplification by APOBEC3G and the Role of HIV-1 Vif (IMAGE)

Okinawa Institute of Science and Technology (OIST) Graduate University

Suppression of Viral Amplification by APOBEC3G and the Role of HIV-1 Vif

Caption

When encapsidated in budding HIV-1 virions, APOBEC3G (A3G) suppresses viral amplification by modifying the viral genome after reverse transcription in infected cells (left). But HIV-1 Vif catalyzes degradation of A3G, leading to infectious virions (right).

Credit

OIST

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