Synthesis scheme (left) and molecular structure (right) of tanzawaic acid B. (IMAGE)

Tokyo University of Science

Synthesis scheme (left) and molecular structure (right) of tanzawaic acid B.

Caption

Researchers from TUS, Japan have synthesized tanzawaic acid B, a promising antibiotic drug candidate, on gram scale, artificially for the first time by utilizing intramolecular Diels-Alder reaction, asymmetric alkylation, and asymmetric Mukaiyama aldol reaction.

Credit

Isamu Shiina from TUS, Japan

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