Action of GDF-15 (IMAGE)

Trophic Communications

Action of GDF-15 — Caption

This foundational research describes a mechanistic link between tumor-produced Growth Differentiation Factor-15 (GDF-15) and the LFA-1/ICAM-1 cell adhesion axis. The interaction between LFA-1/ICAM-1 is a critical step in the infiltration of T cells into the tumor microenvironment.

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