Normal liver organoid and liver tumor organoid (IMAGE)
Caption
Normal liver organoid (left) and liver tumor organoid with mutations introduced by base editing (right). In normal liver organoids, the protein CTNNB1 (yellow) is visible at the cell membrane, on the outside of the cell. In liver tumor organoids, CTNNB1 is present in the nucleus (blue) and cytoplasm of the cells.
Credit
Credit: Shashank Gandhi. Copyright: Hubrecht Institute.
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