Fig. 3 (IMAGE)
Caption
The in vivo role of activin A in osteoclastogenesis in an experimental mouse model of cholesteatoma. INHBA inhibition in fibroblasts reduced osteoclast formation on the parietal bone surface under the cholesteatoma mass. Red, osteoclasts; green, parietal bone surface. Scale bars: 500 µm.
Credit
2023, Masaru Ishii, Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction, Nature Communications
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CC BY