News Release

Bat influenza A viruses use MHC-II for cell entry; this study shows that highly conserved amino acids within MHC-II are key for infection and provide an explanation for the ability of these viruses to target MHC-II from a broad range of vertebrates, inclu

Peer-Reviewed Publication

PLOS

Bat influenza A viruses use MHC-II for cell entry; this study shows that highly conserved amino acids within MHC-II are key for infection and provide an explanation for the ability of these viruses to target MHC-II from a broad range of vertebrates, inclu

image: A group of Jamaican fruit bats (Artibeus jamaicensis), which are a natural host of bat-derived Influenza A viruses. view more 

Credit: Professor Tony Schountz, Colorado State University (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/)

Bat influenza A viruses use MHC-II for cell entry; this study shows that highly conserved amino acids within MHC-II are key for infection and provide an explanation for the ability of these viruses to target MHC-II from a broad range of vertebrates, including humans

#####

In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002182

Article Title: Evolutionarily conserved amino acids in MHC-II mediate bat influenza A virus entry into human cells

Author Countries: Germany, Thailand, the Netherlands, United Kingdom

Funding: see manuscript

Journal

PLoS Biology

DOI

10.1371/journal.pbio.3002182

COI Statement

Competing interests: The authors have declared that no competing interests exist.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.