Fig. 2 (IMAGE) Osaka University Caption AlphaFold prediction of the interaction regions for Tej–Spn-E proteins. Heterodimeric structures of Tej (right, red) and Spn-E (left, blue) are predicted using AlphaFold v2.2. The C-terminal conserved region of Spn-E (blue) predicted to interact with Tej-eSRS (red) was experimentally proven in the Drosophila ovary. Credit 2023, Toshie Kai, Tejas functions as a core component in nuage and precursor processing in Drosophila piRNA biogenesis, Journal of Cell Biology Usage Restrictions Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted. License CC BY-NC-ND Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.